Epitope |
Clone | Epitope mapping |
---|
25G13 | 33-42 | 6E8 | 1-7 | A40 | 35-40 | |
Specificity |
Substance | 25G13 | 6E8 | A40 |
---|
Beta-amyloid (1-42) | + | + | - | Beta-amyloid (1-40) | - | + | + | Amyloid precursor protein | - | - | - | Note:”+” means reaction, “-“ means no cross-reactivity |
Production |
IgG2a for mAb 25G13; IgG2b for mAb 6E8 IgG1 for mAb A40 |
Purification |
Protein A/G affinity column |
Formulation |
50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 |
Storage |
For up to three months at 2-8°C or for up to three years at -25°C~-15°C. Avoid repeated freezing and thawing. |
Platform |
Capture |
Detection |
Analyte |
CLIA |
6E8 |
25G13 |
Beta-amyloid 1-42 |
|
A40 |
6E8 |
Beta-amyloid 1-40 |
|
Target Background |
Beta-amyloid (Aβ or Abeta) are peptides of 36–43 amino acids. They are derived from the amyloid precursor protein (APP) by beta secretase and gamma secretase in human brain. Beta-amyloid 1-42 and Beta-amyloid 1- 40 are related to Alzheimer's disease (AD). |
Note |
GenScript can customize this product per customer's request including product size, buffer components, etc. |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.