Amylin, human, amide

Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin.

产品编号	RP11278
规格	0.5 mg 大单询价
数量
价格	￥1300


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产品概述

Synonyms	Diabetes-Associated Peptide (DAP), amide, humanInsulinoma or islet amyloid polypeptide (IAPP)
Description	Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin.
Cas No	122384-88-7
Sequence	{LYS}{CYS}{ASN}{THR}{ALA}{THR}{CYS}{ALA}{THR}{GLN}{ARG}{LEU}{ALA}{ASN}{PHE}{LEU}{VAL}{HIS}{SER}{SER}{ASN}{ASN}{PHE}{GLY}{ALA}{ILE}{LEU}{SER}{SER}{THR}{ASN}{VAL}{GLY}{SER}{ASN}{THR}{TYR}-NH₂
Sequence Shortening	KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH₂
Molecular Formula	C₁₆₅H₂₆₁N₅₁O₅₅S₂
C Terminal	NH₂
Disulfide Bridge	Cys2-Cys7
Molecular Weight	3903.28

产品属性

Purity	> 95%
Solubility	Can be dissolved in DMSO or DMF first and then dilute with water
Form	Lyophilized
Storage	Store at -20°C. Keep container tightly closed. Store in a cool dry place.